NF Research Initiative

NF Research Initiative

Grant Programs

NFRI-funded Grant Programs

Funds will be awarded to investigators dedicated to advancing NF-related MPNST research, identifying potential for the re-purposing of existing therapies for MPNST treatment, and collaborating with the NF research community to improve clinical treatment and patient outcomes related to MPNST.

All grants provided by the NF Research Initiative have a 10% indirect rate cap.


Two RFAs for MPNST Patient-Derived Model Testing

The purpose of these RFAs is to produce actionable pre-clinical data about response to single agent and combination agents using patient-derived NF1-related MPNST models such as PDX and organoids, with the goal of informing human clinical trials for NF1-related MPNST. These awards will support a project similar to the National Cancer Institute’s PDX_net.


Important Dates:

  • Submit a 1-page letter of intent (LOI) by Thursday, August 22, 2019 at noon EDT

  • Response to LOI (invitation to submit) within 1 week of receipt of LOI

  • Full application (if invited) by October 14, 2019 at noon EDT

  • Award notice: November 27, 2019

  • Funds available as of January 1, 2020 (pending contract)



Children's Tumor Foundation's
Young Investigator Awards

Awarded June 2017 and June 2018

NF Research Initiative's
MPNST Pre-Clinical Research Grant Program

Awarded November 2017