GeM Consortium

Adrienne M. Flanagan, PhD
Royal National Orthopaedic Hospital, United Kingdom

Dr. Adrienne M. Flanagan is a clinical scientist with experience in diagnostic cellular and molecular pathology. Her particular interest is in soft tissue and bone tumor pathology. She has exploited human diseased tissue and the technological developments in nucleic acid with the aim of correlating histological phenotypes with genotypes. This has allowed her identify new biomarkers for classifying disease which has allowed more robust diagnoses to be provided to patients. She is the clinical pathology lead for the largest sarcoma service in the UK. She is also the medical director of the largest diagnostic immunohistochemistry and FISH laboratories in the UK.

Jesse Hart, DO
Lifespan Academic Medical Center/Brown University, Rhode Island

Dr. Jesse Hart is an assistant professor of pathology and laboratory medicine at Brown University and a surgical pathologist at Lifespan Academic Medical Center. He has a particular interest in bone and soft tissue pathology. He provides the majority of diagnostic evaluations of adult sarcoma cases for patients at Lifespan Academic Medical Center, including malignant peripheral nerve sheath tumors (MPNSTs).

Angela C. Hirbe, MD, PhD
Washington University School of Medicine in St. Louis, Missouri

Dr. Angela C. Hirbe is a practicing medical oncologist who treats sarcoma. Her research focuses on utilization of genomic information from sarcomas to better understand the pathogenesis of these tumors and to identify biomarkers and therapeutic targets for these aggressive cancers. Her main interest is in the pathogenesis of malignant peripheral nerve sheath tumors (MPNSTs).

Kevin B. Jones, MD
Huntsman Cancer Institute

Justin T. Jordan, MD, MPH
Massachusetts General Hospital, Massachusetts

Dr. Justin T. Jordan is the associate clinical director of the Pappas Center for Neuro-Oncology at Massachusetts General Hospital (MGH).  Through this affiliation, he routinely evaluates and treats patients with meningiomas, and has developed clinical expertise in the diagnosis and treatment thereof.  He has collaborated with a team of clinical investigators to show an increased risk of cerebrovascular disease among patients with neurofibromatosis, type 1 (NF1).  Additionally, he has worked with a neuropsychology group to investigate patient reported outcomes among patients with NF1, as well predictors of patient satisfaction with NF1.

Raymond Kim, MD, PhD, FRCPC, FACMG
University of Toronto, Sinai Health System, University Health Network, Toronto

Dr. Raymond Kim is currently a medical geneticist at the University Health Network and the Hospital for Sick Children leading their germline cancer genetics program. His current research interests lie in the use of genomic technologies for in hereditary cancer syndromes.  This includes whole genome sequencing and circulating DNA techniques.  He helped establish a multi-disciplinary Neurofibromatosis clinic for adults in Toronto, with a direct link to a pediatric Neurofibromatosis clinic, with a combined size of >300 families.  He is also involved in the sarcoma/soft tissue oncology group in the adult cancer centre at Sinai Health System which is a central referral hub for malignant peripheral nerve sheath tumours.  

David Miller, MD, PhD, FACMG
Boston Children's Hospital, Massachusetts
Director of NF Research Initiative

Dr. Miller is board-certified in Medical Genetics and cares for patients with NF1 in the Multidisciplinary Neurofibromatosis Program at Boston Children’s Hospital where he is the Program Director. He is also currently leading an effort to update the clinical practice guidelines for children with neurofibromatosis, type 1. Dr. Miller’s experience as a clinician who orders genetic tests and provides results directly to patients, combined with expertise in developing and performing clinical laboratory diagnostic assays, provides him with a unique and valuable perspective at the interface of genomic technology and clinical care

Yoshihiro Nishida, MD, PhD
Nagoya University Graduate School of Medicine, Japan

Dr. Yoshihiro Nishida has established, for the first time in Japan, an in-hospital multidisciplinary neurofibromatosis, type1 care network to detect MPNSTs early and initiate early treatment for patients at Nagoya University. As an orthopaedic oncologist, Dr. Nishida has treated patients with MPNSTs with both surgery and chemotherapy. 

Nicole Ullrich, MD, PhD
Boston Children's Hospital, Massachusetts

Dr. Ullrich is an Associate Professor in Neurology and Director of Neurologic Neuro-Oncology at Boston Children’s Hospital. She is a clinical expert in Neurofibromatosis 1, including clinical trials for new drug development. She is the site leader at Boston Children’s Hospital for the Neurofibromatosis Clinical Trials Consortium, one of nine sites in the United States conducting clinical trials for NF1-related tumors.  The goal of this Consortium is to develop novel therapies for patients with neurofibromatosis type 1 (NF1).