NF Research Initiative

NF Research Initiative

MPNST Grant Program

Pre-clinical MPNST Research Grant Program

Awarded in November 2017.


Karen Cichowski, PhD
Professor of Medicine
Brigham and Women’s Hospital

“A chemical-genetic screening and mechanism-based approach to identify effective therapeutic combinations for MPNSTs”


Conxi Lazaro, PhD
Head of the Unit for Molecular Diagnosis, Hereditary Cancer Program
Catalan Institute of Oncology, L’Hospitalet de Liobregat

“Testing combination therapy in an MPNST in vitro/in vivo precision medicine platform”


David Largaespada, PhD
Professor and Associate Director for Basic Research
Masonic Cancer Center, University of Minnesota

“High through-put combinatorial drug and target discovery for NF1-associated MPNST”


Angela Hirbe, MD, PhD
Assistant Professor of Medicine, Medical Oncology, Sarcoma Program
Washington University in St. Louis

“Development of a Preclinical NF-1 MPNST Platform Suitable for Precision Oncology Drug”


Daochun Sun, PhD
*NFRI Early Career Award
Research Fellow, Cancer Biology and Genetics, Director Brain Tumor Center
Memorial Sloan Kettering Cancer Center

“Cancer Stem Cells promote MPNST relapse after chemotherapy”


Yuan Zhu, PhD
Scientific Director, Gilbert Family Neurofibromatosis Institute
Children’s National Medical Center

“Involvement of PRC2 in malignant transformation and metastatic spread of NF1-associated MPNSTs”