NF Research Initiative

Publications and Presentations

Publications and Presentations

Publications by NFRI-funded researchers


The NF Research Initiative’s 2017 MPNST Pre-Clinical Research Grant Program

Dr. Karen Cichowski from Brigham and Women’s Hospital (and affiliated with Harvard Medical School and Dana-Farber/Harvard Cancer Center) has published an article as senior author titled “MAPK Pathway Suppression Unmasks Latent DNA Repair Defects and Confers a Chemical Synthetic Vulnerability in BRAF-, NRAS-, and NF1-Mutant Melanomas” [Link] in the journal Cancer Discovery.



The NF Research Initiative is a proud sponsor of the Children’s Tumor Foundation’s Young Investigator Awards (YIAs).

Lai Man Natalie Wu (2017 YIA recipient) from Cincinnati Children’s Hospital Medical Center has published an article titled “Therapeutic targets for malignant peripheral nerve sheath tumors” [Link] in the journal Future Neurology.

GeM Abstracts and Presentations

Related Publications authored by GeM Collaborators

  • [Link] “Undifferentiated Sarcomas Develop through Distinct Evolutionary Pathways” (Cancer Cell, 2019) by Christopher D. Steele, Maxime Tarabichi,Dahmane Oukrif,Amy P. Webster, Hongtao Ye, Matthew Fittall, Patrick Lombard, Inigo Martincorena, Patrick S. Tarpey, Grace Collord, Kerstin Haase, Sandra J. Strauss, Fitim Berisha, Heli Vaikkinen, Pawan Dhami, Marnix Jansen, Sam Behjati, M. Fernanda Amary, Roberto Tirabosco, Andrew Feber, Peter J. Campbell, Ludmil B. Alexandrov,Peter Van Loo, Adrienne M. Flanagan, and Nischalan Pillay

  • [Link] “A molecular portrait of microsatellite instability across multiple cancers” (Nature Communications, 2017) by Isidro Cortés-Ciriano, Sejoon Lee, Woong-Yang Park, Tae-Min Kim, Peter J. Park

  • [Link] “Linked-read analysis identifies mutations in single-cell DNA-sequencing data” (Nature Genetics, 2019) by Craig L. Bohrson, Alison R. Barton, Michael A. Lodato, Rachel E. Rodin, Lovelace J. Luquette, Vinay V. Viswanadham, Doga C. Gulhan, Isidro Cortés-Ciriano, Maxwell A. Sherman, Minseok Kwon, Michael E. Coulter, Alon Galor, Christopher A. Walsh, and Peter J. Park

  • [Link] “Detecting the mutational signature of homologous recombination deficiency in clinical samples” (Nature Genetics, 2019) by Doga C. Gulhan, Jake June-Koo Lee, Giorgio E. M. Melloni, Isidro Cortés-Ciriano, and Peter J. Park

  • [Link] “Clinical Genomic Profiling Identifies TYK2 Mutation and Overexpression in Patients With Neurofibromatosis Type 1-Associated Malignant Peripheral Nerve Sheath Tumors” (Cancer, 2017) by Angela C. Hirbe, MD, PhD, Madhurima Kaushal, MS, Mukesh Kumar Sharma, PhD, Sonika Dahiya, MD, Melike Pekmezci, MD, Arie Perry, MD, and David H. Gutmann, MD, PhD